Red Dye 40 in Dog Food and Treats: Safety, Side Effects & Alternatives

Quick Facts:

If you've bought brightly colored dog treats—especially vibrant reds and oranges—chances are they contain Red Dye 40, a synthetic petroleum-based colorant. It's the most commonly used artificial color in pet food and treats.

The irony? Dogs can't even see these bright colors the way humans do. Red Dye 40 exists purely for human appeal, not canine health or enjoyment.

This guide explains what Red Dye 40 is, why manufacturers use it, safety concerns, where it's found, and how to avoid it.

What Is Red Dye 40?

Chemical name: Allura Red AC (also called FD&C Red No. 40 or E129 in Europe)

Source: Synthetic azo dye derived from petroleum

Color produced: Bright red to orange, depending on concentration and pH

How it's made: Created through chemical synthesis from petroleum byproducts, not from natural sources like vegetables or fruits.

Why It's Used in Dog Food and Treats

Red Dye 40 serves one purpose: visual appeal to humans. Here's why manufacturers add it:

  1. Consumer expectations: Humans associate bright red/pink colors with meat, freshness, and flavor
  2. Masking poor ingredients: Gray meat meal or by-products become appetizing red "beef" flavor treats
  3. Competitive pressure: Bright colors stand out on store shelves
  4. Cost: Synthetic dyes are cheaper than using quality whole-food ingredients that provide natural color

The truth: Dogs are dichromatic (similar to red-green colorblind humans). They perceive reds and oranges as brownish-yellow. They can't appreciate or care about bright red treats.

If your dog loves a bright red treat, it's the smell and taste (often from artificial flavoring), not the color.

Is Red Dye 40 Safe for Dogs?

The FDA considers Red Dye 40 safe for use in pet food, but "safe" means it won't cause acute toxicity at approved levels—not that it's optimal for health.

Safety Concerns

1. Hyperactivity and Behavioral Issues

In humans: Multiple studies link Red Dye 40 to hyperactivity and attention problems in children. The evidence is strong enough that the European Union requires warning labels on foods containing it.

In dogs: While controlled studies are limited, veterinarians and dog owners report similar patterns:

Mechanism: Azo dyes may disrupt neurotransmitter function or trigger histamine release, affecting behavior.

2. Allergic Reactions

Some dogs are sensitive to artificial dyes, showing:

Food allergy elimination diets often improve when synthetic dyes are removed—sometimes more than removing specific proteins.

3. Carcinogenic Contaminants

The benzidine problem: Red Dye 40 can be contaminated with benzidine and other carcinogenic compounds during manufacturing. The FDA sets maximum contamination limits, but any exposure to known carcinogens raises long-term cancer risk.

Animal studies: Some research shows increased tumor rates in rats exposed to high doses of Red Dye 40, though results are mixed and debated.

4. Regulatory Inconsistencies

Red Dye 40 is banned or restricted in several European countries for human food due to health concerns. The fact that regulations differ so dramatically suggests the safety data isn't as conclusive as the FDA claims.

The Bottom Line on Safety

Red Dye 40 probably won't harm your dog from occasional exposure in small amounts. But:

Given the lack of benefit and potential risks, avoiding Red Dye 40 is a prudent choice.

Where Red Dye 40 Is Found in Pet Products

High-Risk Products

Product Type Likelihood Why
Soft chews/chewy treats Very High Bright red, orange, or multi-colored chews almost always contain Red 40 and other synthetic dyes
Bacon-flavored treats High Red dye creates "bacon" appearance in products with no actual bacon
Beef-flavored treats Moderate-High Red color suggests "real beef" in highly processed products
Kibble with colored pieces High "Variety" kibbles with red/orange bits for visual interest
Colorful bone-shaped chews Very High Bright colors appeal to humans shopping for dogs
Pill pockets and medication treats Moderate Some brands use dyes; check labels carefully
Gravy/topper packets Moderate Brown gravy may contain caramel coloring; red variants may have Red 40

Lower-Risk Products

Other Artificial Colors to Avoid

Red Dye 40 isn't the only synthetic color in pet products. Others to watch for:

Dye Name Color Concerns
Yellow 5 (Tartrazine) Bright yellow Linked to hyperactivity, allergic reactions; banned in some countries
Yellow 6 (Sunset Yellow) Orange Carcinogenic contaminants; allergic reactions; banned in Norway
Blue 1 (Brilliant Blue) Bright blue Possible link to tumors in animal studies; crosses blood-brain barrier
Blue 2 (Indigo Carmine) Blue Brain tumor link in animal studies; banned in some countries
Red 3 (Erythrosine) Cherry red Thyroid tumor link in rats; restricted for cosmetic use
Green 3 (Fast Green) Blue-green Bladder tumor link in animal studies
Caramel coloring Brown May contain 4-MEI, a potential carcinogen

Simple rule: If the ingredient list includes any "FD&C" colors, "Lake" dyes, or numbered colors (Red 40, Yellow 5, etc.), avoid the product.

Natural Alternatives to Synthetic Dyes

Quality pet food manufacturers use whole-food ingredients that provide natural coloring:

Natural Ingredient Color Provided Nutritional Benefits
Beet powder Red to pink Fiber, folate, nitrates for circulation
Paprika Red to orange Vitamin A, antioxidants, anti-inflammatory compounds
Tomato powder Red Lycopene (antioxidant), vitamins C and K
Cranberry powder Red Urinary health, antioxidants, vitamin C
Turmeric Orange-yellow Curcumin (anti-inflammatory), antioxidants
Spirulina Blue-green Complete protein, B vitamins, iron
Carrot powder Orange Beta-carotene (vitamin A), fiber
Spinach/parsley powder Green Vitamins A/K, iron, antioxidants

Even better approach: Let whole-food ingredients determine color naturally:

Quality ingredients don't need artificial enhancement.

How to Avoid Red Dye 40 and Other Artificial Colors

1. Read Ingredient Labels

Look for these terms (all mean synthetic dyes):

Safe phrasings:

2. Visual Inspection

Red flags (literally):

Natural appearance:

3. Choose Minimally Processed Formats

Best options (least likely to contain dyes):

Higher-risk formats:

4. Buy from Brands Committed to Whole Foods

Some brands explicitly avoid all artificial colors, flavors, and preservatives. Look for:

What to Do If Your Dog Has Been Eating Products with Red Dye 40

Don't panic. Most dogs tolerate synthetic dyes without obvious short-term harm. But transitioning to dye-free products is beneficial:

Immediate Steps

  1. Check current treats and food: Read labels for Red 40 and other synthetic colors
  2. Finish current products or discard: Up to you—finishing won't cause acute harm, but discarding eliminates exposure immediately
  3. Replace with whole-food alternatives: Look for naturally colored or single-ingredient options

Monitor for Improvements

Some dogs show noticeable changes 1-3 weeks after eliminating synthetic dyes:

If you notice improvement, it confirms your dog was sensitive to artificial additives.

Share Information

Many dog owners don't realize artificial colors serve no purpose for their pets. Share what you've learned—it helps create market demand for better products.

The Bigger Picture: Why Synthetic Additives Signal Low Quality

Red Dye 40 is rarely the only problem in heavily dyed products. It's usually accompanied by:

Pattern recognition: If a manufacturer uses artificial colors to make a product look appealing, they're likely cutting corners elsewhere too.

Quality brands don't need synthetic dyes because their ingredients speak for themselves.

Learn more: Common Fillers and Binders in Dog Supplements (And Why They're Used)

The Bottom Line

Red Dye 40 exists in dog food and treats for one reason: to make products visually appealing to humans. It provides zero nutritional value, and dogs can't even perceive the bright colors it creates.

Why avoid it:

  1. No benefit: Purely cosmetic for human shoppers
  2. Potential risks: Hyperactivity, allergic reactions, carcinogenic contaminants
  3. Regulatory concerns: Banned in some countries despite FDA approval
  4. Signals low quality: Quality ingredients don't need artificial enhancement
  5. Better alternatives exist: Whole foods provide natural coloring plus nutrition

How to avoid it:

Your dog doesn't care if their treats are bright red. They care about smell, taste, and how the food makes them feel. Choose products that prioritize health over human marketing appeal.

Frequently Asked Questions

Is Red Dye 40 safe for dogs?

Red Dye 40 is FDA-approved for pet food but considered controversial. While acute toxicity is low, concerns include potential links to hyperactivity (documented in children, suspected in dogs), allergic reactions in sensitive dogs, and carcinogenic contaminants (benzidine) found in some batches.

The dye is banned in several European countries for human food. Since it provides no nutritional value and exists purely for human visual appeal (dogs see colors differently), many veterinarians and pet nutritionists recommend avoiding it.

Whole-food ingredients derive natural color from real meat, vegetables, and fruits—no synthetic dyes needed.

What does Red Dye 40 do to dogs?

Red Dye 40 (Allura Red AC) adds bright red/orange color to dog treats and food but provides no nutritional benefit. Potential effects include:

  • Behavioral changes: Hyperactivity, restlessness in sensitive dogs—similar to effects seen in children
  • Allergic reactions: Itching, hives, digestive upset in dogs with sensitivities
  • Digestive issues: Diarrhea, vomiting from artificial additives
  • Accumulation over time: From daily consumption in treats and food

Most dogs tolerate small amounts without obvious symptoms, but chronic low-level exposure effects are unknown. Since dogs perceive color differently than humans and can't appreciate bright red treats, the dye serves only marketing purposes.

What food dyes are toxic to dogs?

No artificial food dyes are acutely toxic to dogs in typical food concentrations, but several raise safety concerns:

  • Red 40 (Allura Red AC): Most common; linked to hyperactivity and allergies
  • Yellow 5 (Tartrazine): Linked to allergic reactions, hyperactivity
  • Yellow 6 (Sunset Yellow): Potential carcinogenic contaminants; banned in some countries
  • Blue 2 (Indigo Carmine): Brain tumor link in animal studies
  • Red 3 (Erythrosine): Thyroid tumor link in rats; restricted in cosmetics
  • Caramel coloring: May contain 4-MEI, a potential carcinogen

Natural colorings (beet powder, turmeric, spirulina) are safe and provide actual nutrients. Best approach: avoid all synthetic dyes—choose products colored only by whole-food ingredients.

Why do dog treats have Red Dye 40?

Dog treats contain Red Dye 40 for human appeal, not canine benefit. Dogs see color differently than humans—they're dichromatic (similar to red-green colorblind humans) and can't appreciate bright reds and oranges.

Manufacturers add dyes because:

  • Humans buy treats based on visual appeal (bright colors suggest freshness/flavor)
  • Dyes mask poor ingredient quality (gray meat meal becomes appetizing red)
  • Color consistency improves shelf presentation
  • Competitors use dyes creating consumer expectation

It's pure marketing. High-quality treats made from whole foods (real meat, organs, vegetables) have natural colors—beef liver is brown, salmon is pink, chicken is tan. Bright artificial colors signal low-quality ingredients and unnecessary additives.

Can Red Dye 40 cause hyperactivity in dogs?

Evidence in dogs is limited but suggestive. In children, multiple studies link Red Dye 40 to hyperactivity and attention problems—strong enough that the EU requires warning labels.

Dog owners and veterinarians report similar patterns: increased restlessness, excitability, difficulty settling, attention problems. However, controlled studies in dogs are lacking.

Mechanism likely involves neurotransmitter disruption or histamine response. Anecdotal evidence is strong: many owners report dramatic behavioral improvements within 1-2 weeks of eliminating artificial dyes.

Given no nutritional benefit and documented hyperactivity link in children, avoiding Red Dye 40 is prudent, especially for already-hyperactive or sensitive dogs.

What are natural alternatives to Red Dye 40 in dog treats?

Natural alternatives provide color from whole-food ingredients:

  • Beet powder (red/pink color) - also provides fiber, nitrates
  • Paprika (red/orange) - contains vitamin A, antioxidants
  • Tomato powder (red) - lycopene, vitamins
  • Cranberry powder (red) - urinary health benefits
  • Turmeric (orange/yellow) - anti-inflammatory curcumin
  • Spirulina (blue-green) - complete protein, vitamins
  • Carrot powder (orange) - beta-carotene, fiber

These natural colorants provide actual nutrition, not just visual appeal. Better approach: let whole-food ingredients determine color naturally—real meat is brown, organs are dark red, salmon is pink, vegetables are green. No colorants needed when using quality ingredients.

How do I avoid Red Dye 40 in dog food?

To avoid Red Dye 40 and other artificial dyes:

  • Read ingredient labels carefully - look for Red 40, Allura Red AC, FD&C Red No. 40, or E129 (European code)
  • Avoid brightly colored treats - bright red, orange, blue treats almost always contain synthetic dyes
  • Choose whole-food-based products - if you can identify real ingredients, it's unlikely to have artificial colors
  • Look for natural coloring - labels like "colored with beet powder" or "turmeric for color"
  • Avoid soft chews and chewy treats - these frequently contain multiple dyes
  • Choose air-dried, freeze-dried, or dehydrated treats - minimal processing means less need for dyes
  • Buy single-ingredient treats - plain beef liver, chicken, or fish have natural colors
Are all artificial colors bad for dogs?

While not all artificial colors are acutely toxic, none provide nutritional value and all carry some risk:

Safety concerns: Potential carcinogenic contaminants (benzidine, 4-aminobiphenyl), links to hyperactivity and behavioral issues, allergic reactions in sensitive dogs, accumulation effects from chronic exposure.

FDA approval ≠ optimal health: These dyes meet safety minimums for preventing immediate toxicity but aren't tested for long-term low-level exposure effects.

Better question: Why use them? Since dogs can't appreciate bright artificial colors and whole-food ingredients provide natural coloring, there's no legitimate reason for synthetic dyes in pet food beyond marketing.

Recommendation: Avoid all synthetic colors (Red 40, Yellow 5/6, Blue 1/2, Green 3, etc.) and choose products colored naturally by real ingredients.

Does organic dog food have Red Dye 40?

No. USDA organic certification prohibits all synthetic food dyes including Red Dye 40. Organic pet foods can only use colors from natural sources like beet powder, turmeric, or inherent ingredient colors.

However:

  • "Natural" ≠ organic - "Natural" labeled foods can still contain synthetic dyes. Check ingredients.
  • "Made with organic ingredients" (less than 95% organic) may allow some synthetic additives
  • Only "100% organic" or "organic" (95%+) guarantees no synthetic dyes
  • Some non-organic foods also avoid dyes - read labels

If budget is limited, prioritize: no synthetic dyes/flavors, whole-food ingredients, minimal processing, quality protein sources—organic is ideal but not mandatory for avoiding Red Dye 40.

Can Red Dye 40 cause cancer in dogs?

Direct evidence in dogs is lacking, but concerns exist:

  • Carcinogenic contaminants: Red Dye 40 can contain benzidine and 4-aminobiphenyl—known carcinogens. FDA sets maximum contamination levels but any exposure raises risk.
  • Animal studies: Some studies in rats and mice show increased tumor rates at high doses, though results are mixed.
  • Regulatory differences: Red Dye 40 is banned for human food in several European countries due to health concerns.
  • Chronic low-level exposure: Unknown long-term effects of daily consumption via treats and food.

The FDA considers Red Dye 40 safe at approved levels, but "safe" means low short-term toxicity, not necessarily optimal for long-term health. Given zero nutritional benefit and potential risks, avoiding synthetic dyes is prudent from cancer prevention perspective.