Glutathione
Last updated: February 11, 2026
Table of Contents
Quick Summary
Glutathione Powerful antioxidant produced naturally in the body. Tripeptide made from three amino acids (glutamine, cysteine, glycine).
What It Is
Powerful antioxidant produced naturally in the body. Tripeptide made from three amino acids (glutamine, cysteine, glycine).
Compare to Similar Ingredients
- vs. glutamine: Glutathione is a tripeptide antioxidant made partly from glutamine. Glutamine is a single amino acid that supports gut and immune health, while glutathione neutralizes free radicals.
- vs. mixed tocopherols: Both are antioxidants. Glutathione is a cellular antioxidant produced in the body, while vitamin E is a fat-soluble vitamin antioxidant obtained from diet.
- vs. ascorbic acid: Both are powerful antioxidants. Glutathione is an endogenous tripeptide that regenerates other antioxidants, while vitamin C is a water-soluble vitamin that also helps regenerate glutathione.
Why It's Used in Dog Products
Manufacturers include glutathione in dog food, treats, and supplements for several reasons:
- Antioxidant and detoxification support
- Supports immune function
- Protects cells from oxidative damage
- Liver health support
Nutritional Profile
Quality Considerations
When evaluating glutathione in dog products, it's important to understand clinical evidence, appropriate dosing, and targeted health benefits. This ingredient's quality and appropriateness can vary significantly based on sourcing, processing, and the specific formula it's used in.
Dogs produce glutathione naturally from amino acids. Supplemental glutathione has poor oral bioavailability—most is broken down in the digestive tract. N-acetylcysteine (NAC) may be more effective for boosting glutathione levels. Used in supplements targeting liver support or detox.
Potential Concerns
While glutathione can be appropriate in dog nutrition, pet owners should be aware of efficacy, quality of source material, and potential interactions with medications. Individual dogs may respond differently to the same ingredient based on their health status, age, and sensitivities.
Naturally produced antioxidant, but oral supplementation has questionable effectiveness due to poor absorption. Dogs synthesize it from dietary protein. Supplementation may benefit dogs with liver disease, but evidence is limited.
Frequently Asked Questions
Is glutathione safe for dogs?
Yes, glutathione is safe for dogs when used appropriately in properly formulated dog food. Generally recognized as safe when used appropriately As with any ingredient, individual dogs may have sensitivities, so monitor for any adverse reactions when first introducing products containing this ingredient.
What does glutathione do in dog products?
Glutathione in dog food. Dog food manufacturers include this ingredient to provide antioxidant and detoxification support and support immune function.
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